THE PROTEIN CHEMISTRY GROUP





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Publications

Meiler A, Klinger C, Kaufmann M (2012): ANCAC: amino acid, nucleotide, and codon analysis of COGs -- a tool for sequence bias analysis in microbial orthologs.
BMC Bioinformatics 12, 223

Kaufmann M, Klinger C (2012): Functional Genomics, Methods and Protocols, Series: Methods in Molecular Biology, Vol. 815, 2nd ed., Springer New York, Dordrecht, Heidelberg, London, ISBN 978-1-61779-423-0.

Kaufmann M (2009): On the free energy that drove primordial anabolism. Invited review.
Int J Mol Sci 10, 1853-1871

Pasdziernik M, Kaltschmidt B, Kaltschmidt C, Klinger C, Kaufmann M (2009): On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y.
BMC Res Notes 2, 102

Meereis F, Kaufmann M (2008): Extension of the COG and arCOG databases by amino acid and nucleotide sequences.
BMC Bioinformatics 9, 479

Kaufmann M (2006): The role of the COG database in comparative and functional genomics.
Curr Bioinf 1, 291

Roßbach M, Daumke O, Klinger C, Wittinghofer A, Kaufmann M (2005): Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold.
BMC Struct Biol 5, 7

Meereis F, Kaufmann M (2004): PCOGR: phylogenetic COG ranking as an online tool to judge the specificity of COGs with respect to freely definable groups of organisms.
BMC Bioinformatics 5, 150

Klinger C, Howe R, Roßbach M, Kaufmann M (2003): Thermophile-specific proteins: the gene product of aq_1292 from Aquifex aeolicus is an NTPase.
BMC Biochem 4, 12

Reichard K, Kaufmann M (2003): EPPS: mining the COG database by an extended phylogenetic patterns search.
Bioinformatics 19, 784-785

Heesche-Wagner K, Schwarz T, Kaufmann M (2001): A directed approach to the selection of bacteria with enhanced catabolic activity.
Appl Microbiol 32, 162-165

Gansser G, Kneist S, Stößer L, Kaufmann M (2000): Differences in acidogenicity of S. sobrinus and S. rattus are linked to the catalytic efficiency of the glycolytic key enzyme phosphofructokinase.
Caries Res 34, 412-417 <

Galinski E, Kaufmann M, Schwarz T, Vangala M (2000): Use of compatible solutes as inhibitors of the enzymatic degradation of macromolecular biopolymers.
European patent EP 1125583

Heesche-Wagner K, Schwarz T, Kaufmann M (1999): Phenol degradation by an enterobacterium: A Klebsiella strain carries a TOL-like plasmid and a gene encoding a novel phenol hydroxylase.
Can J Microbiol 45, 162-171

Kaufmann M, Schwarz T (1999): Ectoine und Verwandte - auf dem Weg zu stabileren Enzymen. pp 163-172 in Industrielle Nutzung von Biokatalysatoren: ein Beitrag zur Nachhaltigkeit / 15. Osnabrücker Umweltgespräche (Hrsg.: Heiden S, Bock A-K, Antranikian G).
Erich Schmidt Verlag GmbH & Co., Berlin, ISBN 3-503-04861-8

Gansser G, Bartholmes P, Kaufmann M, Kneist S, Stößer L (1998): Enzyme der Glykolyse und Laktat-Dehydrogenase aus Streptokokken der mutans-Gruppe zur biochemischen Differenzierung der Virulenz. pp 142-151 in Kariesdynamik und Kariesrisiko (Hrsg: L. Stößer).
Quintessenz Verlags-GmbH, ISBN 3-87652-132-7

Bartholmes P, Heesche-Wagner K, Kaufmann M, Schwarz T (1997): Pocess for microbial decomposition of harmful substances in media charged with harmful substances, and microorganisms suitable for this purpose.
European patent EP 0885032

Kaufmann M (1997): Unstable proteins: how to subject them to chromatographic separations for purification procedures. Review
J Chromatogr B 699, 347-369

Schwarz T, Uthoff K, Klinger C, Meyer HE, Bartholmes P, Kaufmann M (1997): Multifunctional tryptophan-synthesizing enzyme: the molecular weight of the Euglena gracilis protein is unexpectedly low.
J Biol Chem 272, 10616-10623

Bartholmes P, Kaufmann M, Schwarz T (1996): Schadstoffabbau durch optimierte Mikroorganismen: Gerichtete Evolution - eine Strategie im Umweltschutz.
Springer-Verlag Berlin Heidelberg, ISBN 3-540-60705-6

Bartholmes P, Kaufmann M, Schwarz T (1996): Apparatus for recovery and buffer exchange and/or concentration of dissolved macromolecules from a mixture of macromolecules.
European patent EP 0664724

Schwarz T, Bartholmes P, Kaufmann M (1995): Large-scale production of algal biomass for protein purification: tryptophan synthase from Euglena gracilis.
Biotechnol Appl Biochem 22, 179-190

Heesche-Wagner K, Schwarz T, Bartholmes P, Kaufmann M (1995): Purification of unstable proteins from Halobacterium salinarium crude cell extracts. Combined cell disruption and desalting by a hollow fiber membrane module as an access to perform ion-exchange chromatography.
J Chromatogr 711, 175-179

Bartholmes P, Kaufmann M, Schwarz T (1995): Method of culturing micro-organisms under a mutagenic influence.
European patent EP 0748373

Schwarz T, Sindern S, Bartholmes P, Kaufmann M (1994): The use of a hollow fiber membrane module in sample conditioning prior to electrophoresis.
Electrophoresis 15, 1118-1119

Linkens H-J, Bartholmes P, Kaufmann M (1994): The role of the hinge region of the beta-2-subunit in beta-replacement specificity of tryptophan synthase from Escherichia coli.
J Biol Chem 269, 9783-9789

Kaufmann M, Schwarz T, Bartholmes P (1993): Continuous buffer exchange of column chromatographic eluates using a hollow-fibre membrane module.
J Chromatogr 639, 33-39

Kaufmann M, Bartholmes P (1992): Purification, characterization and inhibition by fluoride of enolase from S. mutans DSM 20523.
Caries Res 26, 110-116

Kaufmann M, Schwarz T, Jaenicke R, Schnackerz KD, Meyer HE, Bartholmes P (1991): Limited proteolysis of the beta-2-dimer of tryptophan synthase yields an enzymatically active derivative that binds alpha-subunits.
Biochemistry 30, 4173-4179

Kaufmann M, Schönwald D, Mansouri A, Günther E (1987): Immunological approach to characterize proacrosin and various acrosin forms in boar and man by monoclonal antibodies.
Gamete Res 18, 349-361